"HSC-Protein Mass Fingerprinting" - Improved Sequence Coverage for MALDI-MS protein identification
MALDI-mass-fingerprinting is the method of choice for proteome wide protein identification, combining sub-fmol-sensitivity with sample throughputs of >1000 samples per instrument & day.
A high proteome wide protein ID success rate requires, especially for proteins of smaller size, to avoid any preventible loss of characteristic peptides. Unfortunately, many MALDI-MS gel sample preparation protocols do not address this problem adequately .
Our newly developed High-Sequence-Coverage- protein mass fingerprinting protocol will help you to boost your identification success by exposing more diverse peptides on the Maldi-target, resulting in higher sequence coverage, i.e. higher identification probability and a more significant MASCOT-Score.
Since our HSC-protocol is less complicated than other MALDI-MS sample preparation protocols it is simpler to automate and since it does not involve C18-materials of any kind, it will furthermore ease the strain on your budget for consumables.