Choice of concluded projects
Proteomics marker finding study: Selective identification of proteins induced by known toxins (rat liver, HepG2).
Proteome inventory study: Top 500 expressed proteins in food products.
Proteomics mode of action study: Selective identification of proteins stimulated by an epilepsy drug lead (rat brain).
Proteomics marker finding study: Selective identification of drug targets for COPD (human post mortem lung).
Proteomics marker finding study: Selective identification of drug targets for schizophrenia (human post mortem brain).
Development of strategies to identify >80% of proteins visible after fluorescence stain on a high-resolution 2D-NEPHGE-gel (3-6000 protein spots) using MALDI-MS-fingerprinting.
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